What question did this study set out to answer?

To assess the prognostic significance of CD105 in predicting survival outcomes in oral squamous cell carcinoma (OSCC).

April 23, 2026Journal of Oral Pathology and Medicine0 citations

Prognostic Significance of CD105 ‐Assessed Angiogenesis in Relation to Survival and Clinicopathological Features of Oral Squamous Cell Carcinoma

AGAmol Ramchandra Gadbail MCMinal Chaudhary STSatyajit Ashok Tekade

Key Points

To assess the prognostic significance of CD105 in predicting survival outcomes in oral squamous cell carcinoma (OSCC).
Evaluated CD105 expression levels in oral squamous cell carcinoma samples.
Analyzed correlations between CD105 levels and clinicopathological features.
Higher microvessel density (MVD) associated with CD105 indicates aggressive tumor features and poor prognosis.
CD105 could serve as a target for anti-angiogenic therapies for OSCC.

Abstract

An elevated MVD by CD105 expression is strongly correlated with aggressive HSPL features, stage, nodal metastasis, and poor prognosis in OSCC. In addition to prognostic information, CD105 has the potential to be a target for anti-angiogenic strategies in OSCC indicating its potential use in clinical risk stratification and planning.

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Cite This Study

Gadbail et al. (Mon,) studied this question.

synapsesocial.com/papers/69e9bb9e85696592c86ed3a8 https://doi.org/https://doi.org/10.1111/jop.70142

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