Vitex agnus-castus extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome. | Synapse
April 23, 2026
Vitex agnus-castus extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome.
Key Points
To evaluate the effects of Vitex agnus-castus extract on the endocrine profile and gene expression in rat ovaries affected by polycystic ovary syndrome (PCOS).
Administered Vitex agnus-castus extract to rats with PCOS
Assessed changes in endocrine profile
Analyzed gene expression in ovarian tissues
Notable improvement in endocrine profile following extract administration
Significant changes in gene expression associated with ovarian function
Abstract
The endocrine profile and gene expression were improved in the rat ovary following administration of VE, and therefore, the therapeutic effect of VE may be expected in PCOS.