Cholangiocarcinoma (CCA) is a malignant neoplasm arising from the biliary epithelium and is associated with an exceptionally poor prognosis. Metastasis to long bones is particularly uncommon. A 66-year-old male patient developed femoral metastasis 2 years following a pancreaticoduodenectomy for distal cholangiocarcinoma and subsequently underwent total knee arthroplasty. He experienced a satisfactory postoperative recovery, with a marked enhancement in mobility. This case suggests that radical surgical intervention may be a viable option for metastatic bone disease characterised by isolated lesions. As illustrated in this instance, this therapeutic approach can alleviate symptoms and enhance the quality of life for the remaining duration.
Du et al. (Mon,) studied this question.