Objective To investigate potential diagnostic approaches and therapeutic strategies for renal inflammatory myofibroblastic tumors (IMT). Methods Renal IMT is a rare mesenchymal neoplasm with intermediate malignant potential arising within the urinary system. Its clinical presentation and imaging characteristics are nonspecific; thus, histopathological examination remains the diagnostic gold standard. This article presents a retrospective analysis of the clinical course of a single patient diagnosed with renal IMT. Patient An elderly female presented with intermittent abdominal pain. Abdominal contrast-enhanced computed tomography (CT) revealed a solid mass located in the anterior lip of the right kidney. Following radical right nephrectomy, histopathological evaluation confirmed the diagnosis of renal IMT. Results At the 3- and 6-month follow-up visits postoperatively, the patient showed no evidence of local recurrence or distant metastasis. Conclusion Definitive diagnosis of renal IMT relies exclusively on histopathological assessments. For localized disease, complete surgical resection, preferably radical nephrectomy, is the treatment of choice. In advanced or unresectable cases, tyrosine kinase inhibitors and other targeted agents may be considered as potential therapeutic options.
Zhang et al. (Mon,) studied this question.