Severe numbness of the mouth and tongue induced by piperacillin/tazobactam: a rare case report

Key Points

• To highlight a rare adverse reaction of severe numbness of the mouth and tongue associated with piperacillin/tazobactam.
• Case report detailing symptoms and clinical management
• Monitoring of adverse drug reactions during treatment
• Patient experienced severe numbness after administration of piperacillin/tazobactam.
• Negative skin tests did not predict the adverse reaction.