A novel flow cytometry-based method identified an optimal cut-off value of <25.7% for defining adequate platelet reactivity inhibition with clopidogrel in thrombocytopenic patients.
Cross-Sectional (n=54)
No
Does flow cytometry improve the accuracy of platelet reactivity assessment compared to impedance aggregometry in thrombocytopenic patients on DAPT after PCI?
Flow cytometry may provide a more accurate evaluation of clopidogrel responsiveness than impedance aggregometry in thrombocytopenic patients on DAPT after PCI.
In patients with thrombocytopenia, IA is useful for assessing ASA response, whereas the presented FC method may be more accurate for evaluating response to clopidogrel.
Wilczewska et al. (Tue,) conducted a cross-sectional in Thrombocytopenia in patients undergoing percutaneous coronary intervention (n=54). Flow cytometry (FC)-based platelet reactivity assessment vs. Impedance aggregometry (IA) was evaluated on Optimal cut-off value for flow cytometry to define adequate platelet reactivity inhibition with clopidogrel. A novel flow cytometry-based method identified an optimal cut-off value of <25.7% for defining adequate platelet reactivity inhibition with clopidogrel in thrombocytopenic patients.