Delisting for clinical improvement as a proxy for recompensated cirrhosis on the U.S. liver transplant waitlist: A retrospective cohort study

Key Points

• To investigate the relationship between delisting due to clinical improvement and recompensation in cirrhosis patients on the liver transplant waitlist.
• Analyzed data from the OPTN database for patients listed for liver transplant from 2005 to 2024.
• Categorized delisting due to clinical improvement timing and assessed associated risk factors for relisting.
• Conducted multivariable analysis to identify predictors of relisting after achieving clinical improvement.
• 6.9% of patients achieved delisting due to clinical improvement, with varying rates by liver disease type.
• Only 40.6% of patients improved to Child-Turcotte-Pugh class A after delisting.
• Multivariable analysis indicated that combined improvement in MELD score and CTP class significantly reduced relisting risk.