Global Longitudinal Assessment of MASLD Using Magnetic Resonance Elastography ( GOLDMINE ): A Multi‐Center, International Prospective Cohort Study of Imaging Biomarkers in MASLD Clinical Outcomes

Key Points

• The study aims to validate imaging and blood-based prognostic biomarkers in MASLD using a rigorously phenotyped cohort.
• Conducted a multi-center, international prospective cohort study.
• Utilized advanced MRI-based biomarkers and centralized histology.
• Implemented longitudinal biobanking for outcome assessment.
• Established a phenotype for MASLD through detailed assessment.
• Validated both imaging and blood-based biomarkers' prognostic potential.
• Provided a robust framework for future MASLD research and clinical applications.