This method enables simultaneous estimation of dose and beam width using a single scintillator particle, without requiring complex microdosimetric equipment. It provides a practical and accurate tool for microbeam characterization, contributing to improved dosimetry and targeting precision in radiobiological research at the cellular and subcellular scale. By exploiting emission modulation within a single scintillator particle, beam profiles can be reconstructed with spatial precision beyond the optical pixel resolution.
Yogo et al. (Wed,) studied this question.