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April 25, 2026Immunity Inflammation and Disease0 citationsOpen Access

Predictive Role of Serum Inflammatory Markers in Metastatic Luminal A/B Breast Cancers Receiving CDK‐4/6 Inhibitors Therapy

NBNilüfer BulutSeirei Sakura Citizen Hospital TKTanju KapağanIstanbul Şehir University AÖAykut ÖzmenIstanbul Metropolitan Municipality

Key Points

This research aims to investigate the prognostic impact of serum inflammatory markers in hormone receptor-positive metastatic breast cancer.
Evaluated the association of serum inflammatory markers with treatment outcomes
Assessed levels of LMR in patients receiving CDK-4/6 inhibitors
Cohort study design without observed statistical significance
High LMR levels may indicate predictive and prognostic value regarding treatment selection
No statistical significance was observed in the cohort's overall outcomes

Abstract

The prognostic impact of serum inflammatory markers in hormone receptor-positive metastatic breast cancer is heterogeneous. Although no statistical significance was observed in our cohort, high LMR levels may provide predictive and prognostic value in treatment selection.

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