Intraocular Distribution and Aqueous–Vitreous Correlation of TGF-β Isoforms and GDF-15 in Retinal Diseases

Key Points

• This research aims to explore the distribution patterns of TGF-β isoforms and GDF-15 in different retinal diseases.
• Investigated the intraocular distribution of TGF-β isoforms and GDF-15 across various retinal disease conditions.
• Analyzed the correlation between aqueous humor concentration and posterior segment conditions.
• GDF-15 exhibited a consistent correlation in concentration between aqueous and vitreous humor across different retinal diseases.
• Distinct distribution patterns of TGF-β isoforms were identified based on the type of retinal disease.