Life Course Malaria Exposure and SARS ‐ CoV ‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Key Points

• This study aims to explore the relationship between life-course malaria exposure and SARS-CoV-2 infection in Ugandan adolescents.
• Longitudinal study design within a birth cohort
• Seroepidemiology assessments measuring antibody levels against SARS-CoV-2
• Analysis of malaria exposure history in the cohort
• No consistent evidence found linking life-course malaria exposure with SARS-CoV-2 infection
• Serological measures showed no significant association with antibody levels
• Results suggest malaria exposure does not impact the susceptibility to SARS-CoV-2