Abstract Cold snare polypectomy (CSP) is effective in minimizing delayed postpolypectomy bleeding (DPPB) after resection of pedunculated colorectal polyps. However, robust randomized controlled trial (RCT) evidence remains limited. We aimed to compare the safety of CSP with that of hot snare polypectomy (HSP) for pedunculated polyps. A prospective, multicenter, single-blind RCT was conducted across four endoscopy centers in China. Pedunculated colorectal polyps identified via endoscopy, with heads 15-mm heads in CSP). CSP was associated with a reduced risk of DPPB compared with HSP in pedunculated colorectal polyps with heads ≤15 mm and stalks ≤5 mm, although its applicability to polyps with heads of 16–19 mm remains uncertain.
Wang et al. (Thu,) studied this question.