Subject. The subject of the study is the effect of combined exposure to low–frequency ultrasound and ozone therapy in the complex treatment of lesions of the oral mucosa. Objectives. The aim is to evaluate the clinical effectiveness of using a combined effect of low-frequency ultrasound and ozone therapy in the complex treatment of erosive-ulcerative lesions of the oral mucosa. Methodology. A study was conducted on 60 patients (including 36 patients with chronic recurrent aphthous stomatitis and 24 patients with erosive and ulcerative lesions of the oral mucosa of a post-traumatic nature). Depending on the presence of combined low-frequency ultrasound and ozone therapy in the traditional local treatment regimen for erosive and ulcerative lesions of the oral mucosa, the patients were divided into two groups of 30 patients each (the main group received traditional therapy combined with ozone treatment, while the control group received only traditional therapy). Treatment of each affected area was carried out at a dentist's appointment for 5 minutes, and the treatment course lasted 7 days. The effectiveness of the comprehensive treatment was evaluated in all patients during the treatment process and on the 10th day after the start of treatment. Results. The comprehensive treatment resulted in a more pronounced positive therapeutic effect in the main group compared to the control group. On the 10th day after the start of treatment, the mucous membrane was completely epithelialized in all patients of the main group, but only in 26 (86.7 %) patients of the control group. Conclusion. As a result of the study, the combined effect of ultrasound and ozone therapy was found to be highly effective in the treatment of erosive and ulcerative lesions of the oral mucosa of various etiologies. This was manifested in a rapid reduction of inflammatory symptoms, epithelialization of the affected areas, and a decrease in subjective discomfort, which improved the quality of life for the patients.
Sheregov et al. (Sun,) studied this question.