Hippuric acid–appended aminothiazole derivatives as ion-responsive metallogelators for visual detection of Ce³⁺

Key Points

• This research aims to synthesize and evaluate hippuric acid–appended aminothiazole derivatives as ion-responsive gelators.
• Synthesis of hippuric acid–appended aminothiazole derivatives (1a–4a).
• Evaluation of ion-responsive properties with lanthanides Ce³⁺, Pr³⁺, Sm³⁺, and Eu³⁺.
• Systematic testing of visual detection capabilities in various conditions.
• Successfully synthesized derivatives 1a–4a with ion-responsive behavior.
• Visual detection of Ce³⁺ ions was achieved with high sensitivity.
• Response to other lanthanides was also assessed, indicating broad applicability of the gelators.