A hemostasis management pathway utilizing combined factor concentrates was associated with significantly reduced post-bypass transfusion requirements in pediatric pulmonary artery reconstruction. We observed a higher incidence of post-operative thromboembolism, with a twofold increase at 30 days, although statistical significance was not reached. The majority of post-operative thromboembolism was associated with indwelling lines. Prospective multicenter studies are needed to validate safety, efficacy and generalizability of utilizing combined factor concentrates in pediatric patients.
Flannery et al. (Fri,) studied this question.