Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy | Synapse
April 27, 2026Open Access
Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy
Key Points
The aim is to evaluate the effects of brain-responsive neurostimulation in adults with drug-resistant focal epilepsy.
Participants included adults with refractory focal-onset seizures.
The intervention involved direct brain-responsive neurostimulation.
The follow-up duration extended up to 3 years.
Direct brain-responsive neurostimulation reduced seizure frequency in adults with refractory focal-onset seizures without serious adverse events.
Class IV evidence supports the intervention's safety over the 3-year follow-up.
Abstract
This study provides Class IV evidence that in adults with refractory focal-onset seizures, direct brain-responsive neurostimulation reduces seizure frequency without serious adverse events up to 3 years.