What question did this study set out to answer?

To evaluate the impact of pathological features at intestinal resection margins on recurrence in Crohn's disease.

April 27, 2026Open Access

Severe Myenteric Plexitis at the Proximal Margin Predicts Postoperative Recurrence in Crohn's Disease Irrespective of Margin Distance

Key Points

To evaluate the impact of pathological features at intestinal resection margins on recurrence in Crohn's disease.
Assessed histopathological features of intestinal resection margins in patients with Crohn's disease.
Analyzed the correlation between myenteric plexitis severity and clinical recurrence outcomes.
Severe myenteric plexitis at the proximal margin significantly increased the risk of recurrence (exact metrics not provided).
Pathological findings at the resection margins provide useful prognostic information for postoperative recurrence in Crohn's disease.

Abstract

Objectives: Postoperative clinical recurrence is common in patients with Crohn's disease (CD) despite intestinal resection. Although histopathological findings at resection margins suggestively influence recurrence, their prognostic value remains unclear. This study evaluated the pathological features of the intestinal resection margins in CD and assess their utility in predicting postoperative clinical recurrence.

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