What question did this study set out to answer?

To translate and validate the LT-QOL questionnaire for Brazilian Portuguese speakers after lung transplantation.

April 27, 2026Einstein (São Paulo)0 citationsOpen Access

Translation, cross-cultural adaptation, and validation of the Lung Transplant Quality of Life (LT-QOL) questionnaire for use in adult patients after lung transplantation into Portuguese Brazilian

FRFelipe Farah Pinheiro Rodrigues SSSoraia Micaela Silva GPGrasiani Breggue Pires

Key Points

To translate and validate the LT-QOL questionnaire for Brazilian Portuguese speakers after lung transplantation.
Followed COSMIN recommendations for translation and adaptation.
Assessed internal consistency using Cronbach’s alpha.
Evaluated reliability using intra-rater consistency (ICC) and validity through correlations with SF-36 and SGRQ.
Achieved strong internal consistency (Cronbach’s alpha=0.86).
Demonstrated excellent intra-rater reliability (ICC=0.93).
Showed high convergent validity with SF-36 and good correlation with SGRQ.

Abstract

Highlights ■ First Brazilian Portuguese version of the LT-QOL questionnaire. ■ Translation and cross-cultural adaptation followed COSMIN recommendations. ■ Strong internal consistency (Cronbach’s alpha=0.86). ■ Excellent intra-rater reliability (ICC=0.93). ■ High convergent validity with SF-36 and good correlation with SGRQ. ■ Provides a disease-specific tool for assessing quality of life after lung transplantation in Brazil. ■ Supports future clinical monitoring and research on transplant outcomes. ABSTRACT Objective: To translate, cross-culturally adapt, and validate the Lung Transplant Quality of Life questionnaire ...

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