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Myoblast Therapy Ameliorates Skeletal Muscle Atrophy Resulting From Chronic Denervation | Synapse

April 27, 2026

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Myoblast Therapy Ameliorates Skeletal Muscle Atrophy Resulting From Chronic Denervation

SDShaquielle Dias WPWill Padovano CQChenhu QiuJohns Hopkins University

Key Points

The aim is to evaluate the effects of myoblast therapy on skeletal muscle atrophy due to chronic denervation.
Targeted injection of syngeneic myoblasts into affected skeletal muscles
Assessment of functional and histologic effects post-treatment
Myoblast therapy significantly improved muscle function compared to baseline measurements
Histologic analysis showed marked recovery in muscle tissue structure

Abstract

This data indicates that targeted injection of syngeneic myoblasts can reverse the functional and histologic effects of DIMA in skeletal muscles and is a promising strategy for improving recovery after peripheral nerve injuries.

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Cite This Study

Dias et al. (Sat,) studied this question.

synapsesocial.com/papers/69eefcf4fede9185760d3bd0 https://doi.org/https://doi.org/10.1002/mus.70254