Syringomatous adenoma of the nipple (SAN) is a rare benign tumor of the breast that can become a clinical and diagnostic challenge, as it can be misdiagnosed as invasive carcinoma due to its infiltrative nature. The treatment of choice is wide resection with clear margins. There are limited published cases of SAN. We present a case of SAN in a 42-year-old female patient, with regard to clinical manifestations, histopathologic and surgical findings, and differential diagnosis from other entities. A literature review of histologically confirmed cases of SAN revealed a total of 61 cases, including ours.
Simatos et al. (Sat,) studied this question.