In-Cell Photoactivated Porphyrin Demetalation for Reductive Photodynamic Therapy under Hypoxia.

Key Points

• The central aim is to explore the effectiveness of photoactivated porphyrin demetalation for treating hypoxic tumor cells with photodynamic therapy.
• Utilized photocontrolled porphyrin demetalation
• Applied reductive photodynamic therapy
• Focused on hypoxic tumor cell environments.
• Demonstrated enhanced therapeutic effects in hypoxic conditions
• Achieved significant tumor cell reduction rates under treatment.