What question did this study set out to answer?

To identify a novel NUP98 fusion partner in the myeloid blast phase of chronic myeloid leukemia.

May 2, 20260 citations

Myeloid blast phase of chronic myeloid leukemia with co-occurring t(11;12)(p15;q13)/NUP98::HOXC12: a novel NUP98 fusion partner.

To identify a novel NUP98 fusion partner in the myeloid blast phase of chronic myeloid leukemia.
Identified translocation t(11;12)(p15;q13) involving NUP98 and HOXC12.
Characterized the genetic alterations and their implications in myeloid blast phase.
Identified a new fusion partner NUP98::HOXC12 in the myeloid blast phase.
Highlighted the potential clinical significance of this fusion in CML progression.

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