What question did this study set out to answer?

This research aims to develop a mild and efficient method for the copper-catalyzed trifluoromethylazidation of allenamides.

May 2, 20260 citations

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Copper-Catalyzed Intermolecular Trifluoromethylazidation of Allenamides: An Access to CF3-Containing (E)-Allyl Azides.

JGJiri Gele XSXingyao She YWYì Wáng

Key Points

This research aims to develop a mild and efficient method for the copper-catalyzed trifluoromethylazidation of allenamides.
Utilized copper as a catalyst for the trifluoromethylazidation process.
Tested a broad range of allenamides to assess effectiveness of the method.
Evaluated the synthesis of various CF3-containing compounds.
Successfully synthesized a variety of CF3-containing allyl azides.
Demonstrated efficient method with broad applicability to allenamides.

Abstract

A mild and efficient method for copper-catalyzed intermolecular trifluoromethylazidation of allenamides was explored. This method is effective for a broad range of allenamides and it facilitates efficient synthesis of a wide variety of CF

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Cite This Study

Gele et al. (Wed,) studied this question.

synapsesocial.com/papers/69f594fc71405d493afffd6d https://doi.org/https://doi.org/10.1021/acs.joc.6c00031

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