Multi-omics analysis reveals the alterations in the tumor microbiome and metabolome associated with cervical cancer lymph node metastasis.

) and tumor metabolism. Additionally, our findings suggest a potential trend of phospholipid upregulation in tumor tissues during CC LNM. In summary, our findings underscore the critical role of intratumor microbiota and tumor metabolism in CC LNM, providing valuable insights for developing novel diagnostic markers and therapeutic strategies to address this challenging aspect of cervical cancer. IMPORTANCE: ) and tumor metabolism. This study not only provides valuable insights for developing novel diagnostic markers and therapeutic strategies for CC LNM but also contributes to a deeper understanding of the underlying molecular mechanisms of it.