Cascade Cell-Assisted Enhanced Fluorescence Strategy for Highly Sensitive Detection of Lung Adenocarcinoma Cells in Whole Blood.
Key Points
The aim is to develop a highly sensitive method for detecting lung adenocarcinoma cells in whole blood.
Utilized a cascade cell-assisted enhanced fluorescence strategy for detection.
Designed modular expansion for customization to detect other tumor circulating tumor cells (CTCs).
Achieved detection sensitivity of <0.05 with an AUC of 0.728.
Demonstrated significant potential for diagnostics in lung adenocarcinoma.
Abstract
< 0.05, AUC of 0.728), underscoring its diagnostic potential. Moreover, its modular expandability allows extension to other tumor CTCs detection by replacing target recognition units.