Bioaccessibility and colonic catabolism of carotenoids from mango purée (cv. Osteen): comparison of ileal fluid content and products of in vitro digestion.

Key Points

• The study aims to evaluate the bioaccessibility and colonic catabolism of carotenoids from mango purée.
• In vitro digestion of mango purée was performed with ileal fluid content.
• Compared products of fermentation with intact carotenoids.
• Study registered with ClinicalTrials.gov: NCT06182540.
• A minor fraction of carotenoids remained intact after fecal fermentation.
• Limited colonic availability of carotenoids was suggested based on findings.
• Stability of carotenoids was identified as a key factor influencing bioavailability.