This research aims to assess the antibacterial properties and cytotoxic effects of 5-amino-4-cyano-1,3-oxazole derivatives.
Synthesized new oxazole derivatives and tested their antibacterial activity.
Conducted in silico analysis to predict molecular interactions.
Performed in vitro assays to evaluate cytotoxicity and antibacterial efficacy.
The synthesized compounds exhibited significant antibacterial activity with concentrations of 7.27 ± 1.22 mg/L and 5.10 ± 1.07 mg/L based on classification.
Some derivatives showed lower cytotoxicity, indicating a favorable safety profile for further development.
Abstract
values of 7.27 ± 1.22 and 5.10 ± 1.07 mg/L (D.R. Passino classification).