influx, the nucleic acid constituents ligate into programmable polymer chains that crosslink into barcode-modified condensates. Photoresponsive, caged nucleic acids hybridize with barcode tethers on two distinct organelles, forming a functional two-organelle system in the protocells. Light-induced uncaging releases an information-transfer strand from one organelle, triggering intercommunication and reconfiguration of the partner organelle. By predesigning organelle compositions and transfer strands, the emergence of catalytic DNAzymes or transcriptional machinery in the organelle/protocell assemblies is demonstrated, resulting in dynamic structural reconfiguration of the organelles.
Xue et al. (Fri,) studied this question.