High frequency of CD95 + / CD45RA − regulatory T cells defines an immunosuppressive profile associated with MDS progression

Key Points

• To investigate the association between Treg profiling and risk of MDS progression.
• Analyzed Treg subpopulations in patients diagnosed with MDS.
• Assessed the relationship between Treg profiles and disease progression.
• Evaluated the impact of Treg subpopulations on risk stratification and treatment decisions.
• Identified a higher frequency of regulatory T cells in patients with MDS progression.
• Confirmed that specific Treg profiles indicate an increased risk of disease advancement.