Sustained-release (SR) dosage forms are pharmaceutical formulations designed to release a drug at a predetermined rate in order to maintain a constant drug concentration in systemic circulation for a prolonged period. These systems reduce dosing frequency, improve patient compliance, and maintain therapeutic drug levels while minimizing fluctuations associated with conventional dosage forms. This article discusses the principles, mechanisms, formulation approaches, advantages, limitations, and current advancements in sustained-release drug delivery systems.
Dr. Amit Sharma2 Abhishek Raj*1 (Fri,) studied this question.
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