Pulse Entdecken nav.journalClub Debatten Trends Forschende Zeitschriften

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Start Entdecken nav.journalClub Trends

⌘+K

Electrochemical C3‐Site‐Selective Cyanation of Substituted Indoles | Synapse

May 6, 2026ChemistrySelect0 citations

View Full Paper

Electrochemical C3‐Site‐Selective Cyanation of Substituted Indoles

JKJaswant Kumar SVSaurabh Vijay PPParanjay Parikh

Key Points

To develop an electrochemical strategy for selectively cyanating substituted indoles at the C3 position.
Electrochemical cyanation protocol using TMSCN as a cyano source.
Utilization of a range of protected and unprotected indoles.
Conditions maintained as mild and oxidant-free.
Achieved moderate to good yields of C3-cyano indoles.
Demonstrated good regioselectivity in the cyanation process.

Abstract

ABSTRACT An electrochemical strategy for C3‐site selective cyanation of substituted indoles is reported. This protocol employs TMSCN as a cyano source, yielding C3‐cyano indoles in moderate to good yields. The electrochemical strategy is distinguished by its mild and oxidant‐free conditions, with good regioselectivity. A variety of protected and unprotected indoles has been successfully utilized in this methodology.

KI fragen

Like

Bookmark

Share

View Full Paper

KI fragen

Like

Bookmark

Share

View Full Paper

Cite This Study

Kumar et al. (Fri,) studied this question.

synapsesocial.com/papers/69fa98bd04f884e66b532711 https://doi.org/https://doi.org/10.1002/slct.202600055