with high synthetic efficiency (>90%). Under these conditions, narcissistic chiral self-sorting occurs via dynamic covalent exchange, which results in the formation of homochiral platforms from racemic precursors. The combination of conformationally locked axial chirality, reversible covalent connectivity, and inherent redox activity establishes new amino acid-based motifs as promising modules for constructing chiral Fc-containing porous architectures such as molecular cages, MOFs, and COFs, with potential for asymmetric electrochemical applications.
Konopka et al. (Mon,) studied this question.