Introduction In clinical practice, amblyopia can occur concurrently with ocular disease and structural abnormalities. Foveal hypoplasia is a retinal disorder characterized by incomplete development of the fovea and can coexist with amblyopia. The management and prognosis for visual improvement with amblyopia therapy is complicated by the coexistence of foveal hypoplasia; however, significant improvements in both visual acuity and fusional abilities can be obtained in these cases with the appropriate intervention. Case Reports Three pediatric patients with a history of amblyopia and reduced vision were examined with retinal imaging. In 2 cases, a course of vision therapy improved either visual acuity, binocular skills, or both. A third patient with decreased vision was also evaluated with electrodiagnostic testing, which highlights its role as an adjunctive test when determining a visual prognosis. Conclusion When amblyopia is not improving as expected with standard intervention, foveal hypoplasia should be ruled out with optical coherence tomography, along with other pertinent testing such as electrodiagnostics. Appropriate patient management can improve poor binocular skills in patients with this condition.
McDowell et al. (Tue,) studied this question.