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This research aims to examine how African walnut oil and docosahexaenoic acid affect hematological and oxidative stress markers in a breast cancer model.

May 6, 2026Open Access

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Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on Hematological and Oxidative Stress Markers of Female Wistar Rats With 7,12‐Dimethylbenzaanthracene‐Induced Breast Cancer

Key Points

This research aims to examine how African walnut oil and docosahexaenoic acid affect hematological and oxidative stress markers in a breast cancer model.
Female Wistar rats were induced with breast cancer using 7,12‐dimethylbenz[a]anthracene.
Two treatment groups received either African walnut oil or docosahexaenoic acid for comparative analysis.
Hematological and oxidative stress markers were measured post-treatment.
AWO oil significantly delayed tumor growth compared to control groups.
Increased activities of glutathione peroxidase and superoxide dismutase were observed in AWO oil treated rats.
A reduction in malondialdehyde levels indicated lower oxidative damage with AWO oil.

Abstract

< 0.05) glutathione peroxidase, nitric oxide and catalase activities; and higher superoxide dismutase activity and malondialdehyde levels in the negative control groups. AWO oil could be used in delaying tumor growth, preserving hematological markers and limiting oxidative damage in rats with breast cancer.

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Cite This Study

Djikeng et al. (Thu,) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e483 https://doi.org/https://doi.org/10.1002/fsn3.71821

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