Thermal burns present significant challenges in wound healing and management due to extensive tissue damage and a high risk of infection, which can impede recovery. Such wounds often exhibit deficiencies in essential chemokines and growth factors, necessitating external supplementation to support healing. This article explores the potential role of topical cholecalciferol (vitamin D3) in managing thermal burn wounds. Materials and Methods: This case report describes the treatment of a 35-year-old male with a thermal burn on the dorsal aspect of the right hand. The wound exhibited signs of delayed healing despite standard care. Topical cholecalciferol was applied during routine dressing changes, and the wound's progress was monitored over four weeks. Results: The wound demonstrated significant improvement, with visible evidence of healing and reduced infection risk. Conclusion: Topical cholecalciferol shows promise as an adjunct therapy for enhancing wound healing in thermal burns. However, further studies involving larger patient populations are needed to validate its clinical effectiveness.
Surag et al. (Tue,) studied this question.