What question did this study set out to answer?

The study aims to develop nanocarriers that enhance drug delivery through improved stability and responsiveness.

May 7, 2026Nanoscale0 citations

Thiol-Acrylate Michael Addition Strategy for the Templated Synthesis of Water-Soluble Poly(β-Thioester) Nanogel: Superior Encapsulation Stability and UV-Induced Photolysis Mediated On-Demand Guest Release

AMArun Mondal SSShuvajyoti Sarkar MMMijanur Rahaman Molla

Key Points

The study aims to develop nanocarriers that enhance drug delivery through improved stability and responsiveness.
Developed a thiol-acrylate Michael addition strategy
Synthesized water-soluble poly(β-thioester) nanogels
Evaluated encapsulation stability and responsiveness to UV-induced photolysis
Nanocarriers exhibited superior encapsulation stability
Demonstrated UV-induced photolysis for controlled guest release
Highlighted tumor-selective responsiveness in drug delivery applications

Abstract

The development of nanocarriers that combine high encapsulation stability, tumor-selective responsiveness, and controlled drug release remains a critical challenge in drug delivery application. Herein, we report a smart nanocarrier platform...

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Mondal et al. (Thu,) studied this question.

synapsesocial.com/papers/69fbefc0164b5133a91a3b63 https://doi.org/https://doi.org/10.1039/d6nr00873a

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