“Pregabalin-Loaded Transferosomal Gel for Enhanced Topical Delivery in Peripheral Neuropathy: Formulation, In- Vitro and Ex- Vivo Evaluation”

Key Points

• To develop a transferosomal gel for enhanced topical delivery of pregabalin in managing peripheral neuropathy.
• Developed a transferosomal gel formulation.
• Conducted in-vitro and ex-vivo evaluations of gel performance.
• Assessed sustained release and permeation efficiency.
• The gel exhibited sustained release properties over time.
• Demonstrated effective permeation in ex-vivo tests.
• Showed stability for at least 90 days without irritation.