Metal-Coordination-Driven Self-Assembly of 8-Hydroxyquinoline-Peptide into Hybrid Nanomaterials for In Vitro Multimodal Synergistic Anticancer Activity

Key Points

• The research aims to explore the anticancer potential of hybrid nanomaterials formed from 8-hydroxyquinoline and peptides.
• Developed hybrid nanomaterials through metal-coordination-driven self-assembly of 8-hydroxyquinoline and peptides.
• Assessed the biocompatibility and pharmacological activities of the synthesized nanomaterials in vitro.
• Evaluated the multimodal synergistic effects against cancer cells.
• Demonstrated high biocompatibility of the hybrid nanomaterials.
• Achieved multimodal anticancer activity in vitro, indicating effectiveness against cancer cells.
• Showed enhanced pharmacological activities compared to individual components.