Developmental and cell type‐specific contributions of thalamic serotonin 2A receptors to absence seizures

Key Points

• This study examines how thalamic serotonin 2A receptors affect absence seizures through different cell types.
• Activation of serotonin 2A receptors was assessed in thalamocortical neurons and astrocytes in the ventrobasal (VB) thalamus.
• Comparative analysis focused on the role of receptors in seizure modulation within specific neuron types.
• Activation of serotonin 2A receptors in thalamocortical neurons was found to influence seizure modulation, while astrocytes showed no such effect.