Anti-SARS-CoV-2 response in alveolar blood sample and bronchoalveolar lavage fluid of individuals vaccinated with inactivated COVID-19 vaccines

Key Points

• The aim is to investigate the antibody response in the alveolar blood and bronchoalveolar lavage fluid of individuals vaccinated with inactivated COVID-19 vaccines.
• Examined alveolar blood samples and bronchoalveolar lavage fluid from vaccinated individuals.
• Focused on the presence of anti-N/S IgG, anti-RBD IgG, and anti-N IgA antibodies.
• 92.9% of 14 subjects vaccinated with two or three doses showed positive anti-N/S IgG and anti-RBD IgG in peripheral blood.
• Only 7.1% of subjects tested positive for anti-N IgA in peripheral blood.
• All 14 subjects showed negative results for antibodies in bronchoalveolar lavage fluid.