Ag–Sn@MOFs heterostructure enables ultrasensitive voltammetric determination of vismodegib in serum and urine

Key Points

• This research aims to develop a highly sensitive sensor for detecting vismodegib in biological samples like serum and urine.
• Utilized Ag–Sn@MOFs-modified GCE sensor for detection of vismodegib.
• Achieved detection range from 0.05 to 500 nM and limit of detection at 0.006 nM in serum and urine samples.
• Achieved an ultralow detection limit of 0.006 nM for vismodegib.
• Detection range effectively spans from 0.05 to 500 nM, showing high sensitivity.

Abstract