Objectives/Goals: Navigating uncertainty with emerging technologies used in human research is an ongoing concern for HRPPs and IRBs. This poster aims to describe how collaboration between IRB Offices within a geographic region yields support to address questions and explore possible solutions in a local context. Methods/Study Population: The Southeastern Wisconsin, Clinical and Translational Science Institute (CTSI) includes joint faculty appointments, shared research resources, and various partnerships between researchers and the IRBs of the institutions. In response to increases in projects using AI, one of the partnering institutions inquired with partnering IRB administrators for information on their processes reviewing AI-related research and the connection resulted in monthly meetings between the IRBs. The meetings began with an AI-specific focus but have since developed into a mechanism to support researchers with group members conferring on example submissions and discussing overlapping initiatives. Results/Anticipated Results: This effort has assisted in furthering the mission of the CTSI by lowering barriers to conducting collaborative research. The workgroup partnered to develop a guidance document for researchers seeking to utilize AI in research and for IRB members reviewing the projects. Also, several institutions adapted similar content for protocol submissions, and three implemented consistent questions within the submission forms for research involving AI. In addition, the workgroup has driven individual action at each institution and increased comfort with reaching out to one another for general guidance and advice. Discussion/Significance of Impact: The group was successful in building resources and infrastructure around the review of research utilizing artificial intelligence. A local IRB work group has the potential to address ongoing IRB-related issues and topics within the local context of the geographical region.
Griffin et al. (Wed,) studied this question.