Abstract Background: Clear aligners have gained popularity due to their aesthetics and ease of use compared with fixed appliances. Although initially indicated for mild to moderate malocclusions, they are now increasingly used in complex cases as well. However, their biomechanics and predictability of anterior intrusion remain uncertain, with variable reported efficiency. Therefore, this systematic review evaluates the effectiveness of clear aligners for anterior teeth intrusion and highlights future research on their role in deep bite management. Objectives: The aim of this systematic review was to investigate the intrusion efficiency of clear aligners in correction of deep bite cases. Method: Electronic search of Google Scholar, Scopus, PubMed and Cochrane CENTRAL, along with hand searching of selected orthodontic journals (2005–2025) was performed. Inclusion and exclusion criteria were defined using the PICOS framework. Of 39 identified records, 22 full texts were assessed, and 5 studies met the inclusion criteria. Intrusion efficiency of was evaluated by comparing predicted and achieved intrusion using Clin Check software, CBCT, digital model superimposition and lateral cephalograms. Findings: Results of all studies showed that the predicted intrusion value was more as compared to the actual value with a mean intrusion efficiency ranging between 51% to 73%. Biomechanical control improved with the use of auxiliaries, enhancing anterior intrusive forces. Age influenced outcomes, with greater intrusion observed in adolescents (63.5%) than adults (45.3%), highlighting the need for overcorrection and hybrid mechanics in adults. Despite lower clinical efficiency compared to predictions, clear aligners were effective in deep bite correction at both skeletal and dentoalveolar levels and remain a viable alternative to fixed appliances when appropriate overcorrection is incorporated into aligner software to get required intrusion. Novelty/Significance: This review offers clinically applicable guidance for planning deep bite treatment with clear aligners while emphasizing the need for further research on aligner-mediated tooth movement. Keywords: Clear Aligners, Deep bite, Intrusion of teeth, Aesthetics
Jagtap et al. (Mon,) studied this question.