The aim is to investigate how the G57 (BJ/94-like) H9N2 avian influenza virus replicates and spreads in chickens compared to a G1-B virus.
Comparison of replication rates and tissue dissemination between G57 and G1-B H9N2 viruses in chickens.
Analysis of viral fitness through reassortment involving G57 genotype genes.
The G57 avian influenza virus demonstrated enhanced replication in chickens compared to the G1-B virus.
Increased tissue dissemination was noted with the G57 virus, suggesting greater viral spread.
Abstract
. Although based on prototype viruses, the results suggest that reassortment involving G57 genotype genes could enhance viral fitness and increase animal and human infection risk.