= 60). The dual-modal fusion model demonstrated superior performance over single-modal models in both LN diagnosis and disease activity assessment, achieving notably enhanced sensitivity, specificity, and overall accuracy. Furthermore, dual-modal SERS profiling revealed key biomolecular alterations associated with immune activation, inflammatory responses, and renal injury in children, providing molecular-level insights into the pathophysiological mechanisms underlying cSLE and LN.
Cao et al. (Fri,) studied this question.