Does anticoagulation improve valve hemodynamics in patients undergoing transcatheter valve-in-valve implantation?
Anticoagulation after valve-in-valve TAVI may improve valve hemodynamics at 1 year, though further data are needed to confirm clinical benefits.
Background: Transcatheter aortic valve implantation (TAVI) for prosthetic valve dysfunction is frequently associated with suboptimal echocardiographic outcomes. The effect of anticoagulation on preserving valve function is not well understood. Methods: ), and dimensionless index over time. Results: = .104) at 1-year post-TAVI. Conclusions: Anticoagulation postvalve-in-valve TAVI may lead to lower mean gradients and peak velocities at 1-year follow-up. More data are needed to understand its impact on nonflow-dependent indices and clinical outcomes.
Sethi et al. (Tue,) studied this question.