CT-quantified epicardial adipose tissue volume >108 cm³ predicted sternal wound infection (AUC 0.632, p=0.0135), and thickness >30.5 mm correlated with 30-day mortality (AUC 0.650, p=0.0428).
Cohort (n=325)
Does preoperative CT-quantified epicardial adipose tissue predict postoperative outcomes in patients undergoing isolated CABG?
Preoperative CT quantification of epicardial adipose tissue may serve as a useful prognostic marker for predicting sternal wound infection and 30-day mortality in patients undergoing isolated CABG.
Effect estimate: AUC 0.632
p-value: p=0.0135
PURPOSE: Epicardial adipose tissue (EAT) modulates cardiovascular risk, but its surgical implications remain unclear. We investigated whether CT-quantified EAT predicts postoperative outcomes in isolated coronary artery bypass grafting (CABG) patients. METHODS: This retrospective study analysed isolated CABG patients (2017-2024) with preoperative CT. EAT volume and thickness were measured using semi-automated segmentation. Primary endpoints were correlation of EAT with postoperative clinical outcomes; sternal wound infection, renal insufficiency, cerebrovascular events, postoperative atrial fibrillation (POAF) and other cardiac arrhythmias, and short- and medium-term mortality. RESULTS: The study included 325 patients. EAT volume > 108 cm³ predicted sternal wound infection (AUC = 0.632, 62.5% sensitivity, 63.5% specificity; p = 0.0135). EAT thickness > 30.5 mm correlated with 30-day mortality (AUC = 0.650, p = 0.0428). No association with POAF was observed (p = 0.21). CONCLUSIONS: Quantification of EAT in CABG patients may be a prognostic marker, especially providing risk assessment regarding postoperative sternal infection and short- term mortality.
Dogmuş et al. (Wed,) conducted a cohort in Isolated coronary artery bypass grafting (CABG) (n=325). Epicardial adipose tissue (EAT) quantification by CT was evaluated on Correlation of EAT with postoperative clinical outcomes (sternal wound infection, renal insufficiency, cerebrovascular events, POAF, arrhythmias, mortality) (AUC 0.632, p=0.0135). CT-quantified epicardial adipose tissue volume >108 cm³ predicted sternal wound infection (AUC 0.632, p=0.0135), and thickness >30.5 mm correlated with 30-day mortality (AUC 0.650, p=0.0428).