Local anesthesia alone demonstrated noninferiority to local anesthesia with conscious sedation for the combined primary endpoint at 30 days in patients undergoing TAVI, but resulted in higher anxiety and a 20% conversion rate.
Does local anesthesia alone compared to conscious sedation improve outcomes in patients undergoing TAVI?
While local anesthesia alone for TAVI is noninferior for 30-day clinical outcomes, it is associated with higher patient anxiety, stress, and a 20% crossover rate, questioning its suitability as a patient-centered approach.
Giménez-Milà et al. (Wed,) conducted a letter in Transcatheter aortic valve implantation (TAVI). Local anesthesia alone vs. Local anesthesia with conscious sedation was evaluated on Combined primary endpoint of all-cause mortality, vascular and bleeding complications, infections requiring antibiotics, and neurologic events at 30 days. Local anesthesia alone demonstrated noninferiority to local anesthesia with conscious sedation for the combined primary endpoint at 30 days in patients undergoing TAVI, but resulted in higher anxiety and a 20% conversion rate.