Transcatheter pulmonary valve replacement using a Venus P-Valve was associated with the development of a fast focal ventricular tachycardia (300 b.p.m.) requiring radiofrequency ablation.
Case Report (n=1)
Transcatheter pulmonary valve replacement can be associated with irritative focal ventricular tachycardia originating from the valve, which can be successfully mapped and ablated.
A 17-year-old patient with repaired tetralogy of Fallot underwent transcatheter pulmonary valve (TPV) replacement in December 2024 using a self-expanding Venus P-Valve (Venus Medtech, Hangzhou, China) for severe pulmonary regurgitation associated with significant right ventricular dilatation. Prior to the procedure, no ventricular arrhythmia was documented, and the patient was not receiving any antiarrhythmic medication. In April 2025, an electrophysiological study (EPS) was performed following an episode of exertional syncope to investigate a potential arrhythmic cause. A sustained ventricular tachycardia (VT) was reproducibly inducible. Haemodynamic tolerance was acceptable, allowing rapid high-density activation 3D mapping, which identified a fast (300 b.p.m.) focal VT originating from the proximal part of the TPV ( Panels A and B ; Supplementary material online, Video S1 ). Multiple and prolon-gated irrigated radiofrequency applications were required before tachycardia was no longer inducible. As the patient declined implantable cardioverter-defibrillator implantation
Waldmann et al. (Wed,) conducted a case report in Repaired tetralogy of Fallot with severe pulmonary regurgitation (n=1). Transcatheter pulmonary valve replacement (Venus P-Valve) and radiofrequency ablation was evaluated. Transcatheter pulmonary valve replacement using a Venus P-Valve was associated with the development of a fast focal ventricular tachycardia (300 b.p.m.) requiring radiofrequency ablation.